关键词: 瘴病, 瘴病分布, 历史时期, 人地关系

Abstract: Zhang一disease（瘴），which is an epidemic in the southern part of China in the historical pe-rinds ,is a kind of pernicious malarias .This paper discusses preliminarily the links between this disease and geographical environment。the variations of its distribution and its influence on the so-ciety and economy in the region affected by Zhang一disease. The followings conclusions have been obtained: (1) Zhang一disease is an epidemic which occurs under hot and wet climatic conditions in summer and autumn. (2)In the past 2000 years，the disease was moved slowly to the South. The Northern bound-ary of the region affected by Zhang一disease was Qinlin Mountain and Huaihe River in the War-ring States Period and in the Western Han Dynasty(770BC一AD23)，Daiba Mountain and Changjing River in the sui and Tang Dynasties (AD581一960)，and Nanlin Mountain in the Ming and Qing Dynasties (AD1368一1911).At the present time. Zhang一disease is an epidemic only in the Yunnan Province. One of the main causes the movement of Zhang一desease is the population migration from North to south .Another reason is the change of climate to colder and drier. (3)Zhang一disease influences the society in the region affected in three aspects:population growth，production mode and economic development. These influences resulted in the fact that the northern parts of ancient China were exploited prior to the southern parts.

Key words: Zhang一disease, Zhang一disease distribution, Historic periods, links between Men and Enriroment