Endemic disease or "Water-soil" Diseases mainly originate in regions where water is af-fected by abnormal sulpha,r content. Endemic Diseases may cause illness, disablement or even death. Endemic diseases in China are often found in mountainous areas where the inhabitants are minorities in the most part. In order to control and eliminate these disease, it is necessary to know the distribution of them, their epidemiological characteristics as well as their relationship with the environment.